Plasmid-mediated resistance to the bactericidal effects of normal rabbit serum

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[Mechanisms of plasmid-mediated resistance to quinolones].

Quinolone resistance is caused mainly by chromosomal mutations in gram negative bacteria. In 1998, plasmid-mediated resistance to quinolones in clinical isolates was first reported in a Klebsiella pneumoniae strain. Locus qnr (quinolone resistance) was responsible of the quinolone resistance in this plasmid. qnr codes a protein whose function is protect both DNA-girase and topoisomerase IV from...

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Enterobacteriaceae is a family of bacteria including Escherichia coli and Klebsiella pneumoniae that are common colonizers of the gastrointestinal tract. Extended spectrum βlactamases (ESBL) are bacterial enzymes that degrade β-lactam antibiotics and thus make the bacteria resistant to β-lactam antibiotics. ESBL-producing Enterobacteriaceae (EPE) is an increasing problem constituting a burden o...

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To assess the sensitivity of Gardnerella vaginalis to the complement mediated bactericidal activity of serum, six laboratory strains were incubated with normal human serum and two strains freshly isolated from women with non-specific vaginitis (NSV) were each incubated with homologous patient serum. There was no significant difference between the number of organisms recovered from unheated or h...

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Serum Bactericidal Resistance in Uropathogenic E.coli

Urinary tract infections(UTIs) are among the most common bacterial infections encountered in clinical practice (Ejrnaes, 2011)) E.coli causes about 80%of acute UTIs(Mitsumori,1998).E.coli is the most prevalent facultative gram negative bacilli in the human fecal flora, usually inhabits the colon as an innocuous commensal (Johnson, 1991). E.coli strains causing disease outside the gastrointestin...

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Prevalence of Plasmid-Mediated Quinolones Resistance among Klebsiella pneumoniae Strains Isolated from Hospitals in Borujerd, Iran

ABSTRACT        Background and Objective: Klebsiella pneumoniae is one of the most common causes of bacterial infections. Presence of plasmid-mediated quinolone resistance genes causes low level of resistance in K. pneumoniae. This study investigated the prevalence of resistance to quinolones and fluoroquinolones, and the frequency of qnrA, qnrB and qnrS genes amo...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 1976

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.14.3.848-850.1976